
Terrain First Gut Brain Support: How Foundational Terrain Influences Clarity, Mood, and Emotional Resilience
The gut brain axis is one of the most powerful communication networks in the body. It influences mood, clarity, focus,
You are in the right place. LymePlexPlus.com is now SUPREMEplex®.
Formerly LymePlexPlus.com — Same Team, Same Formulas, New Name: SUPREMEplex®
Daily solutions for resilience, renewal, and gut health—designed for those navigating life after tick-borne challenges.


Daily solutions for resilience, renewal, and gut health—designed for those navigating life after tick-borne challenges.




We know how overwhelming supplement routines can become — especially when brain fog and daily fatigue make everything feel harder.

Traditional Protocol
LP2™

Originally developed to support individuals from serious immune and energy challenges, LP2™ is a liquid formula designed to help restore balance in the body. With a specialized blend of amino acids, enzymes, and peptides, it offers daily support for those seeking to bounce back from prolonged fatigue, inflammation, or post-tick bite imbalance.
Suggested Use:
For those navigating the long-term effects of immune stress or chronic imbalance, LP3™ provides complete microbiome support. Combining prebiotics, probiotics, and postbiotics, it helps repair and maintain gut health—an essential part of restoring energy, clarity, and resilience, especially for those who’ve faced tick-related health challenges.

Every bottle of SUPREMEplex™ LP² is crafted with care and undergoes rigorous third-party testing to ensure purity, potency, and consistency. We are committed to the highest standards of quality and transparency.
Helps promote a healthy internal environment.
Assists the body’s natural ability to manage inflammation, supported in part by the proteolytic enzyme bromelain.
Contributes to the body’s own cleansing processes, aided by NAC (N-Acetyl Cysteine) and L-Glutathione.
Helps contribute to overall immune system wellness.
Provides antioxidant support through naturally occurring L-Glutathione and related compounds
Made with carefully selected, well-researched components including bromelain, NAC, and L-Glutathione.

At SUPREMEplex, we’re on a mission to support your wellness journey through science-backed nutrition and a people-first approach. Our founder, Lori Tran, turned decades of personal health challenges into a passion for creating trusted formulas that help support immune function, gut health, and overall vitality.
What began with our flagship formula, LP2, has grown into a family of products designed to give your body the right tools to thrive—while also empowering others through our affiliate program. We believe in putting People before Profits and offering solutions that encourage both physical and financial well-being.

A true clinician, not a salesman—just results.
A respected and recently retired Lyme-literate M.D., Dr. Gertler has served as our lead research consultant since 2017. Our Founder calls him a “true hero.” With decades of clinical experience and a deep commitment to integrative wellness approaches, Dr. Gertler has brought valuable insight to the development and credibility of SUPREMEplex.
His interest in this work stems from years of seeing wellness challenges—such as those associated with tick-borne illnesses—impact his community. While retired from active practice, he continues to share his expertise in supporting wellness research and education.
“In my experience, LP2 has shown promising potential in supporting overall wellness and quality of life.”
– Dr. Arthur Gertler
SUPREMEplex products are designed to fortify a compromised immune system. Our customers have reported significant increases in their quality of living.
“In my experience with SUPREMEplex™ LP2, I noticed swift symptom relief from Lyme disease and co-infections like Babesiosis within a few days, with air hunger subsiding in a couple of weeks and joint pain improving. I also felt increased energy and flexibility during exercise. After about three bottles (12oz), I regained much of my health and aim to continue for full recovery.*”
Diana
Massachusetts
*Results may vary. This reflects Diana’s personal experience with SUPREMEplex™ LP2 oral and nasal formulas. A high percentage of users report rapid symptom relief for Lyme disease and related conditions, though some may not achieve similar results. Consult your healthcare provider before using for Lyme disease, co-infections, or other health issues.
“After years of struggling with Lyme disease and co-infections, including severe breathing difficulties, hallucinations, heart issues, and body discomfort despite treatments, I started SUPREMEplex™ LP2 oral and nasal formulas and noticed gradual relief from symptoms like pain, eczema wounds on my hands, fatigue, and cognitive challenges. My energy, stamina, mental clarity, and motivation improved, allowing me to resume activities like Pilates. Overall, it supported my path to feeling more like myself again.*”
Elizabeth K.
Berkshire Lyme Alliance, Pittsfield, MA
*Results may vary. This reflects Elizabeth K.’s personal experience with SUPREMEplex™ LP2 oral and nasal formulas. A high percentage of users report symptom relief for Lyme disease and related conditions, though some may not achieve similar results. Consult your healthcare provider before using for Lyme disease, co-infections, or other health issues.
“I used SUPREMEplex™ LP2 nasal spray for a severe headache, and it was relieved in about 10 minutes. Months later, with occasional use, my severe headaches stopped.*”
Laura W.
St. Paul, MN
*Results may vary. This reflects Laura’s personal experience with SUPREMEplex™ LP2 nasal spray. A high percentage of customers report migraine relief within minutes, and many experience reduced frequency with continued use, though some may not see similar results. Consult your healthcare provider before using for migraines or other conditions.

The SUPREMEplex Starter Kit is your all-in-one solution for comprehensive support—especially helpful for those recovering from long-term immune stress or the lingering effects of tick-borne challenges.
Whether you’re just starting your wellness journey or looking to reset your system, this bundle offers everything you need to support resilience from the inside out.
As your body works to restore balance, some people may experience a temporary adjustment period. This is sometimes called the Herxheimer Reaction, or “Herx” for short.
When the body starts receiving targeted nutritional support, it may work harder to process and remove unwanted elements. This temporary phase is a normal part of many wellness journeys and typically eases with time.
For some, this may include:
⚡ Mild Fatigue – A sign that your body is processing and adjusting.
⚡ Temporary Discomfort – Feeling “off” for a short period.
⚡ Fluctuating Energy Levels – Your system is recalibrating.
✅ Stay Hydrated – Drinking water helps flush out unwanted substances.
✅ Nourish with Whole Foods – Supporting your body with clean, nutrient-dense meals.
✅ Prioritize Rest – Give your body time to adjust and recover.
✅ Every journey is unique—listen to your body and give it the support it needs.


When your body is working hard to restore balance, the right daily support can make all the difference. The SUPREMEplex™ Terrain Support Protocol is a simple, structured approach designed to help your body feel more stable, more resilient, and more supported — without overwhelm.
This gentle, terrainfirst framework focuses on:
✔ Nourishing your body with amino acids, peptides, and trace enzymes
✔ Supporting clarity, steadiness, and overall resilience
✔ Encouraging natural detoxification pathways
✔ Helping your body maintain balance day to day
Each step is designed to meet you where you are — whether you’re just beginning your wellness journey or looking for a more grounded, structured approach.
Ready to explore a gentler path forward?
At SUPREMEplex, we understand that healing from Lyme and chronic health challenges takes more than just one approach. That’s why we’ve carefully curated a collection of Complementary Wellness Tools to support your body and mind—every step of the way.
From advanced gut cleanses to light therapy devices that promote mental clarity and relaxation, each product has been selected to work in harmony with your SUPREMEplex protocol.
A wellness blog dedicated to helping you rebuild balance, boost immunity, and support recovery—one day at a time.

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